This study reviews the essential features of the East Africa region, articulating the strategic importance of this region historically. It deals with the historical depth of the Arab-Islamic existence in the horn of Africa region. It also emphasizes the impacts of the European imperialistic heritage in the East African countries. Moreover, this study concerns with both the regional and International powers’ strategies towards this region, with a particular focus on the dynamics of the conflict of hegemony. The study also focuses on analyzing and exploring the strategic intersections between the Gulf region and the East Africa countries.